Effexor

Effexor, also known as venlafaxine HCL, is used to treat depression and other generalized anxiety disorders. It may even be helpful in treating Attention Deficit Disorder and Attention Deficit Hyperactivity Disorder.

Effexor belongs to a group of drugs called Selective Serotonin Reuptake Inhibitors (SSRI), which regulate levels and absorption of serotonin and norepinephrine in the brain.

This drug is available in tablet form, in a variety of dosages. The correct dosage will be determined by your doctor and may take up to a month before the most effective dose is determined. Effexor is typically taken once every 12 hours with a full glass of water, with or without food, or as prescribed by your doctor. It may take several weeks before it is fully effective.

The most frequently reported side effects are loss of appetite, constipation, dizziness, dry mouth, sexual dysfunction, insomnia, nausea, nervousness, sleepiness, sweating and weakness in the muscles. Some patients have experienced elevated blood pressure. Effexor is occasionally used to treat other conditions, as prescribed by your doctor.

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I have been on Effexor XR for almost 4 years. I take an extremely high dose, 450mg daily, but have found it to be my sanity. After months of fertility treatment and three tries with IVF, I got pregnant and had twins. The post partum depression was horrendous to say the least! I thought I was literally going crazy. I have continued to take the meds due to fear of the unknown once weaned. Like the old saying goes, "why fix something that's not broke". There are some drawbacks/side affects, but they are the lesser of the evils. I now enjoy my life, who I am, my beautiful boys that will turn five in only three days, my wonderful husband and my magnificient two older children (20 and 18). I am truly blessed and very thankful for a physician that was willing to listen without judgement and to stick by me to get me back to who I am. Jacksonville, FL
Posted on 3/10/2009 10:41:00 PM by Anonymous
I have been on Effexor XR at 150mg once a day for 4 years and I thank God for it. There is ALWAYS a transitional period with ANY long-term med for depression and/or anxiety. With me- the Effexor caused mild dizziness for the first 6-8 weeks I was on it while my body adjusted- then I was fine. No weight gain- in fact I LOST weight, No sexual dysfunction. The only thing I notice is that I have slightly less patience for people when Im P.M.S.ing which I believe is related to my meds. The thing is- it's kind of like perfume- Chanel #5 may smell great on you because it works well with your body chemistry- not so for me. I'd puke all day if I had to wear Chanel #5! It simply does NOT click with my body chemisrty. Also, with most ssri's there is that 6-8 week trial period while the meds do their thing.We ,as a whole, are SO concerned with that instant fix, the immediate release of depression and panic that 1.) half the people dont even wait out the 1-2 months it takes to get the meds into your system and do its job the right way) and 2.) we expect some kind of "wonder-pill" that's going to fix us right up while we sit back and go about life. The bottom line is- Effexor XR is NOT for everyone, but it IS for me. I also dont expect my meds to do ALL the work. I weather the side effects, what little i do get, but I also follow up with regular visits to both my general doctor and my therapist. I drink alot of water, I work out every day ,I dont drink but I do smoke- because my anxiety is so bad. The Effexor was like a gift from heaven. To all of you having problems- I feel for you . I went through a rough time when i tried Zoloft and Prozac-so I know how you feel. The only advice I can give is- give the meds a chance- take them for the allotted 6-8 weeks and if your symptoms dont let up- then obviously Effexor isnt for you. Effexor is NOT a narcotic- but No medicine should be stopped cold turkey. With care and sympathy for my fellow "Fexxys"- Jennifer New Jersey, U.S.A
Posted on 3/3/2008 1:37:00 PM by Anonymous
I have been on Effexor for about 4 yrs. now. At first I thought it was best thing since bread. First time I didn't feel suicidal. But after being raised to 300 mg., I noticed whenever I took OTC pain meds, I started getting these brain shocks. They're horrible!! I tried getting off and she shocks were unbearable! Bad thing is is that I get headaches everyday now and that's why I was taking any of the OTC pain meds that did not work at all. I read somewhere online that taking the OTC meds and being on a high dose of Effexor will create these brain shocks. My doc is now gradually taking me off of it. I have major depression and anxiety and it scares me that I'll attempt suicide again. But, I can't stand these brain shocks any longer! My GP put me on Firoicet w/codeine, but it doesn't get rid of all the pain. But, it's the best I can get. I've taken hydrocodone from a friend and it got rid of the pain and the zaps! But no doc will give them to me. My psych wants to change my antidepressant to some other class of meds. I was on Zoloft before, which is in the same class, and tried to stop cold turkey and got those brain shocks so bad that I thought I would lose my mind. I believe the longer you are on this class of antidepressant, the worse the side effects get. I would not recommend it to my worst enemy!! Note: I have found that Kratom (a medical herb) that you can order online gets rid of the brain shocks. But, don't abuse it as you may become dependant on it. But, it has been a life saver for me.
Posted on 1/12/2008 9:39:00 PM by Anonymous
I have been on Effexor for over 5 years and after surviving breast cancer in 2006 and having to take Tamoxifen(with its own bag of side effects), I begged my GP to start weaning me off the Effexor. Just taking 75mg less per day has thrown my entire body - mentally and physically- for a loop! I am having difficulty staying on task at work, my appetite is gone, and I have to make myself go workout( I have always been into exercise all my adult life). My sleep is erratic and my dreams are best descibed as bizzarre, but seem so real that I wake up shaking, and usually, dripping wet with sweat! I cannot wait to have this medicine out of my body! Never, ever again would I take this drug or recommend it to anyone. Dallas, TX
Posted on 1/9/2008 11:44:00 AM by Anonymous
I am 32, have been on Effexor xr for almost 2 years, and I am trying to wean. I am experiencing extremely bad dizziness, and vertigo. I also have that shocking sensation in my head and ears. I am so sick on my stomache all I can do is lay down. It is the worst feeling ever. My dreams are so bizzare and when I wake up I feel sore all over and sweaty. I will NEVER take Effexor xr ever again. How long will it take to get completely out of my system and will there be any long term damage from being on this drug and from coming off of it? answers anyone? -North Carolina
Posted on 1/1/2008 2:53:00 AM by Anonymous
I have been on effexor xr twice, the first time not long and had withdrawals when I went off it. This time I have taken it at 150mg for 5 or 6 mos. My memory was poor, tired all the time, like a zombie with no feelings, couldnfunction(m){return ReplaceChar(m)}t even cry if I had to. Now I have slowly weaned off it. And this is just terrible, I have like shock waves going thru my head into my chest. My ears are ringing and feel just weird. My legs starting aching, last nite so bad I could not sleep. I amrritable, scared , I know I will get thru it with my healihng sessions of Reiki, I am a Reiki master, this I believe is the only solution and cure tohelp at this time. We should all work to get this drug of the market now!!! God Bless
Posted on 12/31/2007 10:17:00 AM by Anonymous
I was placed on Effexor by mistake from my new and now "ex doctor". I had been previously on Wellbutrion for the past 2 years. I took the Effexor for 2 1/2 weeks and on the first week, I thought I was doing good, no great! Then I started to have short term memory loss, blurred vision, stomach ache,dizziness, confusion,lost of appetite, unable to sleep, but what really scared me was the realization that at 2 1/2 weeks into it, I no longer had any emotions. I have recently lost my husband and suddenly the pain is gone??? Well, there was no feelings of joy either and to top it all, I was become very angry, enraged to say the least. I quit the Effexor cold turkey and on the 4rth day, I ended up in the ER, completely out of control and suicidal. It has been almost a month now and I am back on Wellbutrion and feeling like a person again. I would caution anyone about taking this poison so called "Effexor". I not only had all of the side effects listed above, but it also made me THINK that dying was an alternative. Good God!! Give me the depression and pain anytime at least I FELT something.
Posted on 12/24/2007 12:21:00 AM by Anonymous
I've only been on this drug for a month or so and I'm experiencing flu like symptoms, I'm assuming from being late on a few doses. My short term memory is on and off, my mouth overproduces saliva, my normal thinking has turned into a fuzzy fake/happy attitude all the time, I'm not able to sleep well, in one week I painted my house, redid my laminate flooring in two rooms and built a bookshelf; a little obsessive behavior that I never had before, I HATE THIS DRUG!
Posted on 12/23/2007 4:46:00 PM by Anonymous
I have been taking Effexor XR for 7 months and have experienced dizziness, short memory loss ( which is negatively affecting my job) blurry vision to the point I can't see for long periods of time...this is not good seeing that I work for an optical center. The itching and bruising started after 2 months. I get a spot that itches real bad and the next day I have a herrendous very dark bruse. I was also taking 1 ecotrin daily heart health because I'm fifty and have a family history of heart disease. My doctor thought it was the aspirin so I stopped taking ecotrin but I still get itching and some brusing. Itching mostly on my scalp. Interesting that I never had that before. Weakness in muscles??? I think everything is heavy now. My girls tell me constantly that I'm much weaker than I used to be, but I still THINK i'm strong and end up hurting myself because my muscles give out. Oh and the weight gain has been herrendous too....34 lbs in less than 3 months. I'm only 5'2" and started at 135 and sky rocketed to 169. I found taking the new Alli diet aid has help me to lose 15 lbs but I'm still in danger of being way overweight (155) for my well being. I was gaining literally 2 lbs every week. My ankles swelled to a lovely size of my calves ( you know the look...cankles) so my doctor put me on a water pill, I have sat here for 2 minutes trying to think of the right word and can only come up with diriveted, directive, oh now I have diuretic. Does anyone have that trouble of thinking of the right words to use??? It's very annoying. It keeps me awake but to a point I feel like I'm not here sometimes, but then again it makes it easier to tune out some people. So the doctor put me on trazadone to help sleep at night and for the pain from fibromyalgia. Oh I forgot to mention that after being on my perfect little concoction for Fibro for 1-1/2 years I quit cold turkey....not recommended at all...these were my meds at that time.. (elavil <amitriptiline> for sleep, wellbutrin SL to level serotonin, relafen for joints and sometimes flexeril for musle pain, but I survived after a month of stomach aches, pain and disorientation. I forgot to refill my script for 3 days and only experienced the stomach ache and very nauseated. That went away within 2 hours after taking an Effexor. I can't imagine going off of this drug after reading all of these comments. I want to but now I'm real scared. Oh well I guess the pros and cons will have to work themselves out. Wish me luck. Good news is my hot flashes have decreased immensely which I had been having for 3 years ( early menopause, total hysterectomy) so I'm glad for that relief.. I feel so bad for all of us taking this med, without the major side effects it would be alright. Like most of you said...they should list this stuff in BIG LETTERS and really enforce Doctors to warn about what happens when you try to stop taking Effexor.
Posted on 12/21/2007 10:28:00 AM by Anonymous
I have been on and off with Effexora for years. I am struggling with the weight gain. ( I came from 110 lb to 125lb in just a year). It makes me terribly ichy, bruise once in a while and hive fever almost everyday. I know it is addicted but I don't do well without it. I am trying get off again.
Posted on 12/18/2007 2:26:00 AM by Anonymous
I was taking Effexor XR 37.5ml for 3 1/2 years and intended to wean myself off but it didnt happen that way...long story short, I stopped cold turkey two weeks ago. I have not expeirenced any of the symptoms listed under withdrawals but find I am slightly irritated over certain minor things but that doesnt last long. Effexor was wonderful and gave me a whole new life when I first started taking it. It is sad that American citizens are always ready to sue someone's ass off.....no one shoves medication down our throats. We, as the patient, are responsible to make our own decisions regarding what we put into our bodies.
Posted on 12/17/2007 2:02:00 PM by Anonymous
my 19 year old son has been on Effevor xr for almost a year. he was depressed and suffering from anorexia. we went through 5 different drugs before the effexor xr helped. or so I thought, he still seems sad and dull also his pupils are always dialated. he wants to get off but the doctor is reluctant to help. he was suicidal coming off other drugs he was on for only a few months. I am really worried about this one. why doesn't Effexor ex have a "discontinue dosage" kit? maybe because they do not want anyone to ever get off of it?
Posted on 12/16/2007 2:47:00 PM by Anonymous
I to was put on Effexor for hot flashes. I have been on the medication for several years. It has helped some. I have also experienced less anxiety. I have missed a dosage here and there and within approximately 24 to 36 hours I feel very strange - some vertigo and feeling very disorenited - not able to formulate thoughts - I was not told about these side effects. I am ready to get off the medication and knowing what happens to me without it in just a day or two makes this path very scary - If you have not started it - DON'T EVER!
Posted on 12/8/2007 7:58:00 AM by Anonymous
I have been on Effexor xr 150 for about two years, I would appreciate any advice on how to get off of it, I had a terrible anxiety attack when forgot to take a pill for 36 hours. It scared the living daylights out of me, also I am having more and more dizziness and disorientation. HELP!!! Class action sounds good to me. J.
Posted on 12/4/2007 7:39:00 PM by Anonymous
Took myself off effexor--can hardly walk. am more clear-headed than the whole time I was on it. Count me in on class action. never ceased depression--just learned to act.
Posted on 12/2/2007 8:54:00 PM by Anonymous
i have been on effexor XR for over 6 years now and i have had to come off and on the drug due to priscriptions costing too much, but i never had any of these symptoms thats anyone is discussing.....i had some of those problems with other brands like prozak and paxil but not effexor...i guess it all depends on the person, not all pills work for everyone and you have to try a few before you find one that works....i recommend effexor but it may not work for you personally....thanks for listening and just be patient you will eventually find a prescription that works best for yourself.
Posted on 11/30/2007 9:57:00 PM by Anonymous
My pain doctor prescribed this for me without telling me what it was. I don't suffer from major depression and never have. When I asked him what it was, he said, "Just take it!" Since I'd just had major back surgery AND was about to start chemotherapy, I didn't have the energy to research this medication. While I'm sure it works well for people who are clinically depressed, the side effects that someone who is not can have while on this medication are pretty scary (and not only that, but some of the symptoms put my job in jeopardy). Fortunately I'm off it now. Lesson learned: KNOW what you're taking before you put any medication in your mouth!
Posted on 11/29/2007 5:46:00 PM by Anonymous
I just started taking it a couple of days ago. You guys are scaring me. I didn't want anything that would cause weight gain,took Paxil and before I knew it the pounds were adding on. Got them all off once quit taking it.Taking Effexor though has made me feel nervous,and not able to sleep. Does that go away? I am on the lowest dosage now for 8 days then work my way up in dosage.
Posted on 11/28/2007 4:37:00 PM by Anonymous
I've been on it for about 8 months...strictly for hot flashes. I am now trying to get off of it and I am miserable. dizzy, hot flashes, can barely walk without crashing into walls. Very disoriented. Afraid to drive. difficult to work. I strongly recommend NOT STARTING THIS horrible drug. No hot flashes were ever this bad. ls, Texas
Posted on 11/26/2007 6:09:00 PM by Anonymous
I amin the process of weening off Effexor. I dropped the doseage from 150mg to 37.5 mg over the past two weeks. I was fine until two days ago when I completely stopped. I have the worst vertigo, nausea, and insomnia ever! How long can I expect this to continue?
Posted on 11/24/2007 10:54:00 AM by Anonymous
I have been on Effexor XR for about two years. I am now trying to ween off of it and it is the worst experience of my life! The pain, insomnia, and headaches are terrible! I would have never agreed to start taking it in the first place had I known it would be this bad. I had no warning of these side effects from my Dr. I would love a class action suit on this one!
Posted on 11/22/2007 11:59:00 AM by Anonymous
As venlafaxine is very hard to come off of, I wouldn't take it for anything that's not necessary. I get withdrawal when I only miss one day.
Posted on 11/20/2007 11:30:00 PM by Anonymous
I had been on effexor xr for 6years. I have been coming off of it for 3 weeks. Nausea vert1go headacke trouble with speech. also I am depressed. I have started on Prozac . What needs to be done is to have the side effect out there so you can see what to look forward to if you come off the med.
Posted on 11/10/2007 11:30:00 PM by Anonymous
I have been taking Effexor 150mg for a few months now. My doctor has increased it about 2 months back to 300mg. Not only was my head on fire with the pain, but I was seeing things and hearing voices. I took myself back down to the 150mg to now only last week find myself when I went out with my sister to black out on the dancefloor and have no recongnition of doing so. Only time I knew something was wrong was when I woke up in the hospital. Now my doctors have me seeing a neurologist because they feel I had a seizure. What next???? Death..... is that the next step. My doctor won't let me get off this insanity ride until I see the specialist. I want to do something now!!!!!! I guess I am on my own and the medical field should be banning this type of medication from ever be selling if it is this hard to come off of. Yours Truly The fuzzy eyed zombie.
Posted on 11/9/2007 9:11:00 PM by Anonymous
Can this medication cause itching and bruising to occure
Posted on 10/25/2007 8:00:00 PM by Anonymous
Does this drug cause addiction
Posted on 10/13/2007 8:27:00 PM by Anonymous
Is this a narcotic drug
Posted on 10/13/2007 8:25:00 PM by Anonymous
I have been trying to get off this medication for over a month now and I have just spent the worst week of my life withdrawing from this med. Its not bad enough that it causes such horrific pain and suffering but even the medical community treats you like you are over reacting or something. I even had one doctor who called it anxiety. You know this is criminal. This company should be put out of business and I wouldnt be surprised if they didnt have class action suits pending. I for one and going to pursue that possiblity.
Posted on 8/3/2007 7:55:00 AM by Anonymous
A search in the top left box appears to produce some results for Venlafaxine.
Posted on 7/24/2007 6:11:00 PM by Anonymous
Why, if the GENERIC name is Venlafaxine, can I not get the GENERIC version of EFFEXOR XR, which would greatly reduce my pharmacy spending?
Posted on 7/24/2007 3:55:00 PM by Anonymous